PUBMED Search
2023
Meir A, Raina VB, Rivera CE, Marie L, Symington LS, Greene EC.
Nat Commun. 2023 Dec 8;14(1):8144. doi: 10.1038/s41467-023-43918-4.
PMID: 38065943
Mechanism of target site selection by type V-K CRISPR-associated transposases.
George JT, Acree C, Park JU, Kong M, Wiegand T, Pignot YL, Kellogg EH, Greene EC, Sternberg SH.
Science. 2023 Nov 17;382(6672):eadj8543. doi: 10.1126/science.adj8543.
PMID: 37972161
Structural insights into BCDX2 complex function in homologous recombination.
Rawal Y, Jia L, Meir A, Zhou S, Kaur H, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Taylor AB, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, Wasmuth EV, Greene EC, Sung P, Olsen SK.
Nature. 2023 Jun 21. doi: 10.1038/s41586-023-06219-w.
PMID: 37344589
Single-molecule visualization of Pif1 helicase translocation on single-stranded DNA.
Mustafi M, Kwon Y, Sung P, Greene EC.
J Biol Chem. 2023 May 11;299(6):104817. doi: 10.1016/j.jbc.2023.104817.
PMID: 37178921
2022
Repair of mismatched templates during Rad51-dependent Break-Induced Replication.
Choi J, Kong M, Gallagher DN, Li K, Bronk G, Cao Y, Greene EC, Haber JE.
PLoS Genet. 2022 Sep 2;18(9):e1010056. doi: 10.1371/journal.pgen.1010056. eCollection 2022 Sep.
PMID: 36054210
Bloom helicase mediates formation of large single-stranded DNA loops during DNA end processing.
Xue C, Salunkhe SJ, Tomimatsu N, Kawale AS, Kwon Y, Burma S, Sung P, Greene EC.
Nat Commun. 2022 Apr 26;13(1):2248. doi: 10.1038/s41467-022-29937-7.
PMID: 35473934
Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments.
Meir A, Crickard JB, Kwon Y, Sung P, Greene EC.
Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2113871119. doi: 10.1073/pnas.2113871119.
PMID: 35042797
Warren GM, Meir A, Wang J, Patel DJ, Greene EC, Shuman S.
Nucleic Acids Res. 2022 Jan 25;50(2):952-961. doi: 10.1093/nar/gkab1270.
PMID: 34967418
2021
Mechanistic Insights From Single-Molecule Studies of Repair of Double Strand Breaks.
Kong M, Greene EC.
Front Cell Dev Biol. 2021 Nov 15;9:745311. doi: 10.3389/fcell.2021.745311. eCollection 2021.
PMID: 34869333
Single-molecule studies of yeast Rad51 paralogs.
Roy U, Kwon Y, Sung P, Greene EC.
Methods Enzymol. 2021;661:343-362. doi: 10.1016/bs.mie.2021.08.006. Epub 2021 Sep 10.
PMID: 34776219
Editorial overview: Recombination - the ends justify the means.
Greene EC, Rothstein R.
Curr Opin Genet Dev. 2021 Nov 8:S0959-437X(21)00122-2. doi: 10.1016/j.gde.2021.10.003. Online ahead of print.
PMID: 34764004
Computed structures of core eukaryotic protein complexes.
Humphreys IR, Pei J, Baek M, Krishnakumar A, Anishchenko I, Ovchinnikov S, Zhang J, Ness TJ, Banjade S, Bagde SR, Stancheva VG, Li XH, Liu K, Zheng Z, Barrero DJ, Roy U, Kuper J, Fernández IS, Szakal B, Branzei D, Rizo J, Kisker C, Greene EC, Biggins S, Keeney S, Miller EA, Fromme JC, Hendrickson TL, Cong Q, Baker D.
Science. 2021 Nov 11:eabm4805. doi: 10.1126/science.abm4805. Online ahead of print.
PMID: 34762488
The Role of the Rad55-Rad57 Complex in DNA Repair.
Roy U, Greene EC.
Genes (Basel). 2021 Sep 8;12(9):1390. doi: 10.3390/genes12091390.
PMID: 34573372
Srs2 and Pif1 as Model Systems for Understanding Sf1a and Sf1b Helicase Structure and Function.
Meir A, Greene EC.
Genes (Basel). 2021 Aug 26;12(9):1319. doi: 10.3390/genes12091319.
PMID: 34573298
DNA Repair Pathway Choices in CRISPR-Cas9-Mediated Genome Editing.
Xue C, Greene EC.
Trends Genet. 2021 Apr 22:S0168-9525(21)00053-6. doi: 10.1016/j.tig.2021.02.008. Epub 2021 Apr 22.
PMID: 33896583
Single-Stranded DNA Curtains for Single-Molecule Visualization of Rad51-ssDNA Filament Dynamics.
Roy U, Greene EC.
Methods Mol Biol. 2021;2281:193-207. doi: 10.1007/978-1-0716-1290-3_11.
PMID: 33847959
Clutch mechanism of chemomechanical coupling in a DNA resecting motor nuclease.
Unciuleac MC, Meir A, Xue C, Warren GM, Greene EC, Shuman S.
Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2023955118. doi: 10.1073/pnas.2023955118.
PMID: 33836607
RADX controls RAD51 filament dynamics to regulate replication fork stability.
Adolph MB, Mohamed TM, Balakrishnan S, Xue C, Morati F, Modesti M, Greene EC, Chazin WJ, Cortez D.
Mol Cell. 2021 Jan 8:S1097-2765(20)30957-6. doi: 10.1016/j.molcel.2020.12.036. Online ahead of print.
PMID: 33453169
The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination.
Roy U, Kwon Y, Marie L, Symington L, Sung P, Lisby M, Greene EC.
Mol Cell. 2021 Jan 4:S1097-2765(20)30938-2. doi: 10.1016/j.molcel.2020.12.019. Online ahead of print.
PMID: 33421364
Xue C, Molnarova L, Steinfeld JB, Zhao W, Ma C, Spirek M, Kaniecki K, Kwon Y, Beláň O, Krejci K, Boulton SJ, Sung P, Greene EC, Krejci L.
Nucleic Acids Res. 2021 Jan 11;49(1):285-305. doi: 10.1093/nar/gkaa1184.
PMID: 33332547
2020
Demystifying the D-loop during DNA recombination.
Roy U, Greene EC.
Nature. 2020 Oct 14. doi: 10.1038/d41586-020-02831-2. Online ahead of print.
PMID: 33057188
Crickard JB, Kwon Y, Sung P, Greene EC.
EMBO J. 2020 Oct 15;39(20):e105705. doi: 10.15252/embj.2020105705. Epub 2020 Aug 13.
PMID: 32790929
DNA Curtains Shed Light on Complex Molecular Systems During Homologous Recombination.
Meir A, Kong M, Xue C, Greene EC.
J Vis Exp. 2020 Jun 23;(160). doi: 10.3791/61320.
PMID: 32658186
Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination.
Crickard JB, Moevus CJ, Kwon Y, Sung P, Greene EC.
Cell. 2020 Jun 11;181(6):1380-1394.e18. doi: 10.1016/j.cell.2020.04.056. Epub 2020 Jun 4.
PMID: 32502392
Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA.
Kong M, Cutts EE, Pan D, Beuron F, Kaliyappan T, Xue C, Morris EP, Musacchio A, Vannini A, Greene EC.
Mol Cell. 2020 Jul 2;79(1):99-114.e9. doi: 10.1016/j.molcel.2020.04.026. Epub 2020 May 22.
PMID: 32445620
2019
Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast.
Yan Z, Xue C, Kumar S, Crickard JB, Yu Y, Wang W, Pham N, Li Y, Niu H, Sung P, Greene EC, Ira G.
Mol Cell. 2019 Dec 5;76(5):699-711.e6. doi: 10.1016/j.molcel.2019.08.017. Epub 2019 Sep 18.
PMID: 31542296
Jia N, Unciuleac MC, Xue C, Greene EC, Patel DJ, Shuman S.
Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24507-24516. doi: 10.1073/pnas.1913546116. Epub 2019 Nov 18.
PMID: 31740608
Xue C, Daley JM, Xue X, Steinfeld J, Kwon Y, Sung P, Greene EC.
Nucleic Acids Res. 2019 Dec 2;47(21):11225-11237. doi: 10.1093/nar/gkz810.
PMID: 31544923
Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination.
Steinfeld JB, Beláň O, Kwon Y, Terakawa T, Al-Zain A, Smith MJ, Crickard JB, Qi Z, Zhao W, Rothstein R, Symington LS, Sung P, Boulton SJ, Greene EC.
Genes Dev. 2019 Sep 1;33(17-18):1191-1207. doi: 10.1101/gad.328062.119. Epub 2019 Aug 1.
PMID: 31371435
The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments.
Crickard JB, Xue C, Wang W, Kwon Y, Sung P, Greene EC.
Nucleic Acids Res. 2019 May 21;47(9):4694-4706. doi: 10.1093/nar/gkz186.
PMID: 30916344
Helicase Mechanisms During Homologous Recombination in Saccharomyces cerevisiae.
Crickard JB, Greene EC.
Annu Rev Biophys. 2019 May 6;48:255-273. doi: 10.1146/annurev-biophys-052118-115418. Epub 2019 Mar 11.
PMID: 30857400
Regulatory control of Sgs1 and Dna2 during eukaryotic DNA end resection.
Xue C, Wang W, Crickard JB, Moevus CJ, Kwon Y, Sung P, Greene EC.
Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6091-6100. doi: 10.1073/pnas.1819276116. Epub 2019 Mar 8.
PMID: 30850524
Crickard JB, Kwon Y, Sung P, Greene EC.
J Biol Chem. 2019 Jan 11;294(2):490-501. doi: 10.1074/jbc.RA118.006146. Epub 2018 Nov 12.
PMID: 30420424
2018
The biochemistry of early meiotic recombination intermediates.
Crickard JB, Greene EC.
Cell Cycle. 2018;17(23):2520-2530. doi: 10.1080/15384101.2018.1553355. Epub 2018 Dec 10.
PMID: 30482074
New roles for RAD52 in DNA repair.
Xue C, Greene EC.
Cell Res. 2018 Dec;28(12):1127-1128. doi: 10.1038/s41422-018-0105-8. No abstract available.
PMID: 30367126
Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase.
Crickard JB, Kaniecki K, Kwon Y, Sung P, Greene EC.
Proc Natl Acad Sci U S A. 2018 Oct 9. pii: 201810457. doi: 10.1073/pnas.1810457115. [Epub ahead of print]
PMID: 30301803
Biochemical attributes of mitotic and meiotic presynaptic complexes.
Crickard JB, Greene EC.
DNA Repair (Amst). 2018 Nov;71:148-157. doi: 10.1016/j.dnarep.2018.08.018. Epub 2018 Aug 23. Review.
PMID: 30195641
De Tullio L, Kaniecki K, Greene EC.
Methods Enzymol. 2018;600:407-437. doi: 10.1016/bs.mie.2017.12.004. Epub 2018 Feb 1.
PMID: 29458768
Regulation of Hed1 and Rad54 binding during maturation of the meiosis-specific presynaptic complex.
Crickard JB, Kaniecki K, Kwon Y, Sung P, Lisby M, Greene EC.
EMBO J. 2018 Apr 3;37(7). pii: e98728. doi: 10.15252/embj.201798728. Epub 2018 Feb 14.
PMID: 29444896
Spontaneous self-segregation of Rad51 and Dmc1 DNA recombinases within mixed recombinase filaments.
Crickard JB, Kaniecki K, Kwon Y, Sung P, Greene EC.
J Biol Chem. 2018 Mar 16;293(11):4191-4200. doi: 10.1074/jbc.RA117.001143. Epub 2018 Jan 30.
PMID: 29382724
A change of view: homologous recombination at single-molecule resolution.
Kaniecki K, De Tullio L, Greene EC.
Nat Rev Genet. 2018 Apr;19(4):191-207. doi: 10.1038/nrg.2017.92. Epub 2017 Dec 11. Review.
PMID: 29225334
2017
Kaniecki K, De Tullio L, Gibb B, Kwon Y, Sung P, Greene EC.
Cell Rep. 2017 Dec 12;21(11):3166-3177. doi: 10.1016/j.celrep.2017.11.047.
PMID: 29241544
The condensin complex is a mechanochemical motor that translocates along DNA.
Terakawa T, Bisht S, Eeftens JM, Dekker C, Haering CH, Greene EC.
Science. 2017 Nov 3;358(6363):672-676. doi: 10.1126/science.aan6516. Epub 2017 Sep 7.
PMID: 28882993
BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.
Zhao W, Steinfeld JB, Liang F, Chen X, Maranon DG, Jian Ma C, Kwon Y, Rao T, Wang W, Sheng C, Song X, Deng Y, Jimenez-Sainz J, Lu L, Jensen RB, Xiong Y, Kupfer GM, Wiese C, Greene EC, Sung P.
Nature. 2017 Oct 19;550(7676):360-365. doi: 10.1038/nature24060. Epub 2017 Oct 4.
PMID: 28976962
De Tullio L, Kaniecki K, Kwon Y, Crickard JB, Sung P, Greene EC.
Cell Rep. 2017 Oct 17;21(3):570-577. doi: 10.1016/j.celrep.2017.09.073.
PMID: 29045827
Pokhrel N, Origanti S, Davenport EP, Gandhi D, Kaniecki K, Mehl RA, Greene EC, Dockendorff C, Antony E.
Nucleic Acids Res. 2017 Sep 19;45(16):9413-9426. doi: 10.1093/nar/gkx598.
PMID: 28934470
Sequential eviction of crowded nucleoprotein complexes by the exonuclease RecBCD molecular motor.
Terakawa T, Redding S, Silverstein TD, Greene EC.
Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6322-E6331. doi: 10.1073/pnas.1701368114. Epub 2017 Jul 17.
PMID: 28716908
Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex.
Ma CJ, Kwon Y, Sung P, Greene EC.
J Biol Chem. 2017 Jul 14;292(28):11702-11713. doi: 10.1074/jbc.M117.794545. Epub 2017 May 27.
PMID: 28551686
Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases.
Lee JY, Steinfeld JB, Qi Z, Kwon Y, Sung P, Greene EC.
J Biol Chem. 2017 Jun 30;292(26):11125-11135. doi: 10.1074/jbc.M117.787614. Epub 2017 May 5.
PMID: 28476890
Replication Protein A Blocks the Way.
Greene EC.
Biochemistry. 2017 Apr 4;56(13):1809-1810. doi: 10.1021/acs.biochem.7b00221. Epub 2017 Mar 23. No abstract available.
PMID: 28333436
Ma CJ, Gibb B, Kwon Y, Sung P, Greene EC.
Nucleic Acids Res. 2017 Jan 25;45(2):749-761. doi: 10.1093/nar/gkw1125. Epub 2016 Nov 29.
PMID: 27903895
Telomere Recognition and Assembly Mechanism of Mammalian Shelterin.
Erdel F, Kratz K, Willcox S, Griffith JD, Greene EC, de Lange T.
Cell Rep. 2017 Jan 3;18(1):41-53. doi: 10.1016/j.celrep.2016.12.005.
PMID: 28052260
Single-Stranded DNA Curtains for Studying Homologous Recombination.
Ma CJ, Steinfeld JB, Greene EC.
Methods Enzymol. 2017;582:193-219. doi: 10.1016/bs.mie.2016.08.005. Epub 2016 Oct 22.
PMID: 28062035
2016
Taylor MRG, Špírek M, Jian Ma C, Carzaniga R, Takaki T, Collinson LM, Greene EC, Krejci L, Boulton SJ.
Mol Cell. 2016 Dec 1;64(5):926-939. doi: 10.1016/j.molcel.2016.10.020. Epub 2016 Nov 17.
PMID: 27867009
ATP hydrolysis Promotes Duplex DNA Release by the RecA Presynaptic Complex.
Lee JY, Qi Z, Greene EC.
J Biol Chem. 2016 Oct 14;291(42):22218-22230. Epub 2016 Sep 1.
PMID: 27587394
Visualizing recombination intermediates with single-stranded DNA curtains.
Qi Z, Greene EC.
Methods. 2016 Aug 1;105:62-74. doi: 10.1016/j.ymeth.2016.03.027. Epub 2016 Mar 30. Review.
PMID: 27038747
Generalized nucleation and looping model for epigenetic memory of histone modifications.
Erdel F, Greene EC.
Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4180-9. doi: 10.1073/pnas.1605862113. Epub 2016 Jul 5.
PMID: 27382173
DNA Sequence Alignment during Homologous Recombination.
Greene EC.
J Biol Chem. 2016 May 27;291(22):11572-80. doi: 10.1074/jbc.R116.724807. Epub 2016 Apr 15. Review.
PMID: 27129270
Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin.
Stigler J, Çamdere GÖ, Koshland DE, Greene EC.
Cell Rep. 2016 May 3;15(5):988-98. doi: 10.1016/j.celrep.2016.04.003. Epub 2016 Apr 21.
PMID:27117417
On the influence of protein-DNA register during homologous recombination.
Greene EC.
Cell Cycle. 2016;15(2):172-5. doi: 10.1080/15384101.2015.1121352.
PMID: 26652653
2015
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.
Redding S, Sternberg SH, Marshall M, Gibb B, Bhat P, Guegler CK, Wiedenheft B, Doudna JA, Greene EC.
Cell. 2015 Nov 5;163(4):854-65. doi: 10.1016/j.cell.2015.10.003.
PMID: 26522594
DNA RECOMBINATION. Base triplet stepping by the Rad51/RecA family of recombinases.
Lee JY, Terakawa T, Qi Z, Steinfeld JB, Redding S, Kwon Y, Gaines WA, Zhao W, Sung P, Greene EC.
Science. 2015 Aug 28;349(6251):977-81. doi: 10.1126/science.aab2666. Erratum in: Science. 2015 Oct 30;350(6260):aad6940.
PMID: 26315438
The Dynamics of Eukaryotic Replication Initiation: Origin Specificity, Licensing, and Firing at the Single-Molecule Level
Duzdevich D, Warner MD, Ticau S, Ivica NA, Bell SP, Greene EC..
Mol Cell. 2015 May 7;58(3):483-94. doi: 10.1016/j.molcel.2015.03.017. Epub 2015 Apr 23.
PMID: 25921072
A Molecular Take on Aesop's The Oak and the Reeds.
Moevus CJ, Greene EC.
Cell. 2015 Mar 12;160(6):1039-40. doi: 10.1016/j.cell.2015.02.036.
PMID: 25768898
DNA Sequence Alignment by Microhomology Sampling during Homologous Recombination.
Qi Z, Redding S, Lee JY, Gibb B, Kwon Y, Niu H, Gaines WA, Sung P, Greene EC.
Cell. 2015 Feb 26;160(5):856-69. doi: 10.1016/j.cell.2015.01.029. Epub 2015 Feb 12.
PMID: 25684365
2014
Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules.
Gibb B, Ye LF, Kwon Y, Niu H, Sung P, Greene EC.
Nat Struct Mol Biol. 2014 Oct;21(10):893-900. doi: 10.1038/nsmb.2886. Epub 2014 Sep 7.
PMID: 25195049
Collins BE, Ye LF, Duzdevich D, Greene EC.
Methods Cell Biol. 2014;123:217-34. doi: 10.1016/B978-0-12-420138-5.00012-4. Review.
PMID: 24974030
Lee JY, Finkelstein IJ, Arciszewska LK, Sherratt DJ, Greene EC.
Mol Cell. 2014 Jun 5;54(5):832-43. doi: 10.1016/j.molcel.2014.03.033. Epub 2014 Apr 24.
PMID: 24768536
RPA antagonizes microhomology-mediated repair of DNA double-strand breaks.
Deng SK, Gibb B, de Almeida MJ, Greene EC, Symington LS.
Nat Struct Mol Biol. 2014 Apr;21(4):405-12. doi: 10.1038/nsmb.2786. Epub 2014 Mar 9.
PMID: 24608368
Visualizing protein movement on DNA at the single-molecule level using DNA curtains.
Silverstein TD, Gibb B, Greene EC.
DNA Repair (Amst). 2014 Aug;20:94-109. doi: 10.1016/j.dnarep.2014.02.004. Epub 2014 Mar 2.
PMID: 24598576
Gibb B, Ye LF, Gergoudis SC, Kwon Y, Niu H, Sung P, Greene EC.
PLoS One. 2014 Feb 3;9(2):e87922. doi: 10.1371/journal.pone.0087922. eCollection 2014.
PMID: 24498402
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
Sternberg SH, Redding S, Jinek M, Greene EC, Doudna JA.
Nature. 2014 Mar 6;507(7490):62-7. doi: 10.1038/nature13011. Epub 2014 Jan 29.
PMID: 24476820
DNA dynamics and single-molecule biology.
Duzdevich D, Redding S, Greene EC.
Chem Rev. 2014 Mar 26;114(6):3072-86. doi: 10.1021/cr4004117. Epub 2014 Jan 8. Review. No abstract available.
PMID: 24400809
2013
How do proteins locate specific targets in DNA?
Redding S, Greene EC.
Chem Phys Lett. 2013 May 10;570. doi: 10.1016/j.cplett.2013.03.035.
PMID: 24187380
Tension modulates actin filament polymerization mediated by formin and profilin.
Courtemanche N, Lee JY, Pollard TD, Greene EC.
Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9752-7. doi: 10.1073/pnas.1308257110. Epub 2013 May 28.
PMID: 23716666
Molecular traffic jams on DNA.
Finkelstein IJ, Greene EC.
Annu Rev Biophys. 2013;42:241-63. doi: 10.1146/annurev-biophys-083012-130304. Epub 2013 Feb 28. Review.
PMID: 23451891
Target search dynamics during post-replicative mismatch repair.
Gorman J, Greene EC.
Cell Cycle. 2013 Feb 15;12(4):537-8. doi: 10.4161/cc.23669. Epub 2013 Jan 23. No abstract available.
PMID: 23343769
2012
Towards physiological complexity with in vitro single-molecule biophysics.
Duzdevich D, Greene EC.
Philos Trans R Soc Lond B Biol Sci. 2012 Dec 24;368(1611):20120271. doi: 10.1098/rstb.2012.0271. Print 2013 Feb 5. Review.
PMID: 23267187
Wang F, Redding S, Finkelstein IJ, Gorman J, Reichman DR, Greene EC.
Nat Struct Mol Biol. 2013 Feb;20(2):174-81. doi: 10.1038/nsmb.2472. Epub 2012 Dec 23.
PMID: 23262491
Sliding to the rescue of damaged DNA.
Gibb B, Greene EC.
Elife. 2012 Dec 13;1:e00347. doi: 10.7554/eLife.00347.
PMID: 23240090